Health Article Center

Health Article Center


Aspirin and colon cancer

Posted: 24 Oct 2010 07:28 AM PDT

 Aspirin and colon cancerPeople often low-dose aspirin, the risk for colon cancer by 24 per cent drop increase, according to a new study finds.

Who has the low-dose aspirin , but not the disease, their risk of death can be reduced by one-third, the researchers said.

Study lead author, at least data provides strong support for anti-cancer potential of aspirin.

“This is proof that low-dose aspirin prevents cancer,” said Dr. Peter Rothwell, professor of neurology at the hospital, John Radcliffe at Oxford University in Great Britain.

Random bits are kept mainly tumors as well as songs of screening colonoscopy, “he said.

Patients at increased risk of colon cancer than those with a family history of previous polyps, low-dose aspirin, take the long-term believes Roth.

“This is another benefit of aspirin helps cancer risks and the benefits for healthy people who take low-dose aspirin choose balance,” he added.

The report, published in the October 21 online issue of The Lancet.

prevent the ability of aspirin on vascular disease and the effects of aspirin on colorectal cancer reviews to investigate – The study team analyzed Rothwell data from four randomized clinical trials.

Four studies included more than 14,000 people with aspirin or placebo for an average of six years to be treated. During the 18 years average follow-up of 2.8 percent had developed colorectal cancer, the researchers found.

The collection of data from all the evidence calculated Rothwell Group that consumption of low-dose aspirin reduced for 20 years, the risk of colon cancer by 24 percent.

In addition, those who developed colorectal cancer by taking aspirin, the risk of death from the disease declined by 35 percent.

These effects were consistent across experiments, a dose of 75 mg aspirin per day. High doses of aspirin does not seem to add benefit presented by researchers.

The researchers also found the absolute risk reduction of 20 fatal colon cancer after five years of those 75 took place mg to 300 mg of aspirin per day. The high risk of about 3.5 percent in those taking placebo and 1.5 percent for recipients of aspirin showed the data.

Seventy per cent reduction on colorectal cancer and deaths were on a smaller number of tumors on the right side of the colon to the proximal colon, but not the effect of aspirin cancer appears in the lower part of the colon fall called the distal colon, only a limited impact on colon cancer, said researchers.

Most colon cancers arise from polyps, and screening flexible sigmoidoscopy and colonoscopy, the risk of reducing the removal of these polyps. However, screening is not 100 percent effective, particularly proximal colon cancer, they added.

Dr. Robert Benamouzig, Department of Gastroenterology, Avicenne Hospital, Bobigny, France and author of an accompanying journal, said that people had with normal risk for colon cancer does not start, preventing colon cancer aspirin.

“But if you are at high risk, yes, you have to take low-dose aspirin,” he said. “Right now the evidence seems stronger for people at high risk, but not for people with average risk.”

How aspirin might work to reduce the risk of colorectal cancer can not be reduced to reduce fully known, but due to the ability of aspirin to reduce inflammation, said Benamouzig.

The disadvantage of a daily dose of aspirin is a potential risk of gastrointestinal bleeding. So before you should begin an aspirin regimen you consult with your doctor, experts say.

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