Parkinson’s disease is really a progressive, disabling condition which occurs because of losing dopaminergic neurones in specific regions of mental performance the substantia nigra as well as the locus ceruleus. It can be characterised by gradually increasing rigidity, bradykinesia, postural instability and tremor. Treatment solutions are palliative, and a number of medicines can be obtained. [...]

In 1993, the final AAN Practice Parameter on treatment of Parkinson's disease (PD) figured levodopa was the very best medicine for management of the disorder. Ever since then, numerous new compounds including non-ergot dopamine agonists (DA) and sustained-release levodopa happen to be released and studied. Thus, the problem of treatment in de novo PD patients [...]

Parkinson's disease is attributable to the death of only a few nerve cells that produce the chemical dopamine. Without dopamine, movement doesn’t seem possible. All creatures from fruit flies to people use dopamine within their brains to manage movement. Normally, an individual has in regards to a half million dopamine-producing cells positioned in a place [...]