Health Article Center |
The search for understanding gene causes fatal brain tumor Youth Posted: 16 Dec 2010 02:50 PM PST U.S. scientists discovered the genetic code, the most common form of brain tumors in children. Gene Sequence found that medulloblastoma tumor or MB, much less of the genetic abnormalities similar to adults tumors. View that the MB five to 10 times less than the mutations in solid tumors of adults can continue to try to understand what triggers of cancer and more effective treatment. “The good news is that for the first time we now have the gene fragments of cancer identified in childhood and found that with MD, there are only a few fragments,” said lead author Dr. Victor Velculescu professor at the University of Sidney Kimmel Comprehensive Cancer Center at the University of C. Johns Hopkins University in Baltimore. “And this means that the potential is easier to stop and intervene,” he said, comparing the cancer train accelerated out of control. Velculescu and colleagues, their results online 16th December in the number of their science report said the first time that genetic decoding was applied to – older growth. Every year cancer affects 1 in 200 000 children under 15. Before passing through the central nervous system of the patient, MBS in the cerebellum of the brain responsible for balance and control of complex motor activity beginning. Focus on childhood cancer was 88, the team-specific mutations in tumors 225 mega samples, much smaller than the number of tumors in adults. That surprised researchers because previous work suggested a large genetic difference between children and adult malignancies. The discovery could help the way MB is classified and treated. “We now have the pieces that have changed in this particular form of cancer,” says Velculescu. “And that’s what we do is to understand how these pieces together in new ways for targeted therapies exploit these differences to be determined may have to be made.” At least one expert agrees Dr. Isabelle M. Germano, director of the Brain at Mount Sinai Medical Center in New York that the search for new section allows researchers to the deadly disease. “In theory, this study – is that because fewer mutations may be easier for these mutations target states – the hope of a better way to deal with mega-growth,” said Germano. “So this is to increase understanding of what we face. After hearing you, and the underlying mechanisms of this disease, it is possible to develop treatments … or, if possible, prevent and also that it is first line, “he said. Although the disease is rare in the 10-20 percent of the MB primary tumors in children, “said Germano. “The results were actually improve as we learn more, with a five-year survival rate is about 80 percent of the patients was in the 3 years. “But children [survival rate five years] only 30 percent,” he said. “So the death of a moment can be very high. |
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