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research: drug diabetes and lung disease Posted: 02 Nov 2010 08:42 AM PDT can can control frequently used medications for diabetes such as metformin and help prevent lung cancer, U.S. researchers reported on Tuesday. Patients, the drugs to compensate for diabetes are much less likely to have lung cancer to spread – that is, if it is more lethal – the researchers told a meeting of the American College of Chest Physicians. Metformin, a generic is available and cheaper, has powerful new drugs called thiazolidinediones, TZDs or glitazones, the researchers said. “Our study, like other studies found an association between metformin and / or use of TZD and the risk of lung cancer show,” says Dr. Peter Mazzone of the Cleveland Clinic in Ohio, who led the study. “But only in this study, we can help signal less advanced cancer, that cancer, a decreased incidence of squamous cell carcinoma and small cell lung cancer improves survival for stage-controlled patients treated with metformin and / or TZD.” The team studied the medical records of 157 lung cancer survivors with diabetes. Those who had drug or metformin or TZD had significantly less advanced lung cancer that has spread – 20 percent taking the drug has spread their cancer, compared to 42 percent of them. “The trend we have seen starting TZDs protection of metformin,” said Mazzone. TZD in GlaxoSmithKline Avandia, rosiglitazone, as known, and the competing drug Actos, or pioglitazone, from Takeda Pharmaceutical Ltd. Mazzone said it could one day metformin prevent lung cancer in smokers. But Dr. David hikers, president of the American College of Chest Physicians, said that further studies are needed before they are proposed. Metformin is one of the most common medications for diabetes type 2, with 41 million prescriptions in the U.S. in 2008, said the American College of Chest Physicians, in a statement. In May, researchers reported drug called iloprost, for treatment of pulmonary hypertension also prevent lung cancer inhaled allowed. In April, the researchers said that food derived called natural supplements – Inositol Mayo seems to stop pre-cancerous changes lead to lung cancer. Lung cancer is the number one cancer killer in the world, killing 1.2 million people per year. Only 15 percent of people diagnosed with lung cancer live five years later, in part because the disease is spreading mostly in silence for years before causing symptoms, it is clear enough to be discovered. |
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